Pathology MCQPathology MCQ
CAN YOU GUESS THE TYPE OF LEIOMYOMA BASED ON THE MORPHOLOGY?
Female Genital Pathology

CAN YOU GUESS THE TYPE OF LEIOMYOMA BASED ON THE MORPHOLOGY?

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Difference between fumarate hydratase deficient leiomyoma and leiomyoma with bizzare nucleiDM HistopathologyDM OncopathologyFumarate hydratase deficient leiomyomaINI-SS DM HISTOPATHOLOGYINI-SS DM Histopathology mcqsINI-SS HISTOPATHOLOGY MCQSLeiomyoma with bizzare nucleiMCQ for DM HistopathologyMcqs for NEET-SS OncopathologyNEETSS OncopathologypathologypathologymcqPGIMER DM Histopathology

Here are a few images, all you got to do is to guess the type of genetic mutation in the leiomyoma just based on the morphology.

Focus on the nucleus...
Spindle to oval shaped nucleus with bright eosinophilic nucleoli surrounded by a halo.
See those rhabdoid eosinophilic inclusions?

What do you think the type of leiomyoma is?

A. Leiomyoma with bizzare nuclei

B. Fumarate hydratase deficient leiomyoma

C. Cellular leiomyoma

D. Mitotically active leiomyoma

ANSWER

The correct answer is B- Fumarate hydratase deficient leiomyoma.

Option A: Leiomyoma with bizzare nuclei does not have an eosinophilic nucleoli.

Option C: Cellular leiomyoma is more cellular than the adjacent myometrium.

Option D: Mitotically active leiomyoma has a mitosis of > 4-10/ HPF

DIFFERENCE BETWEEN FUMARATE HYDRATASE DEFICIENT LEIOMYOMA AND LEIOMYOMA WITH BIZZARE NUCLEI

Difference between leiomyoma with bizzare nuclei and fumarate hydratase deficient leiomyoma.
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