Based on WHO 2022 Tumors of the Female Genital Tract.
1. CONVENTIONAL- SPINDLE CELL LEIOMYOSARCOMA
2 or more of the following
- Marked cytologic atypia
- Tumor cell necrosis
- >= 10 mitosis / 10 HPF (High power field) OR >= 4 mitosis/mm2
2. EPITHELIOID LEIOMYOSARCOMA
1 or more of the following
- Moderate to severe cytologic atypia
- Tumor cell necrosis
- >= 4 mitosis / 10 HPF (High powers field) OR >=1.6 mitosis/mm2
3. MYXOID LEIOMYOSARCOMA
1 or more of the following
- Moderate to severe cytologic atypia
- Tumor cell necrosis
- >= 1 mitosis / 10 HPF (High power field) OR > 1 mitosis/mm2
- Infiltrative borders/ irregular margins.
Try to answer the MCQ below
Which of the following is true regarding leiomyosarcomas?
Correct answer is Mitotic count essential for the diagnosis of Myxoid Leiomyoma is >1/10 HPF
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